Zannos Melathron Hotel

Elegant 18th- and 19th-century villa-hotel overlooking Santorini and the surrounding islands from a timeless medieval village. The final five-minute approach is on foot, with donkeys carrying luggage up through a maze of narrow cobbled walkways. Rich fabrics, antique furnishings, murals and original oils distinguish the handsomely transformed 18th-century interior, which contains 10 well-equipped suites with high ceilings and stucco walls; romantic outdoor/indoor dining room; terrace loggia bar; and cigar lounge. A small sea-facing swimming pool, spa and beauty treatments, and a Santorini wine-tasting experience complete the picture. Closed November through April.